A NOVEL, DOUBLE-ASYMMETRIC ALDOL APPROACH TO THE SYNTHESIS OF A 1β-METHYL CARBAPENEM ANTIBIOTIC PRECURSOR

DOI: 10.1016/S0040-4039(00)82373-4

Source and publish data:

Tetrahedron Letters p. 6461 - 6464 (1988)

Update date:2022-08-03

Topics:

Authors:

Shirai, Fumiyuki

Nakai, Takeshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)82373-4

A novel synthetic approach to the 1β-methyl carbapenem key precursor is described which involves the chelation-controlled double-asymmetric aldol reaction as the key step.

Full text of DOI:10.1016/S0040-4039(00)82373-4

Products guided by the article

Product name:C₂₇H₅₁NO₅Si₂

Cas No:122553-24-6

R&D Labs maybe for 122553-24-6

Anhui Xinyuan Technology Co.,Ltd

Contact:0086-559-3515800

Address:No.16 Zijin Rd, Circular Economic Zone, Huizhou District, Huangshan Anhui China
Chemsky（shanghai）International Co.,Ltd.

Contact:0

Address:0
Chemvon Biotechnology Co. Ltd.

website:http://www.chemvon.com

Contact:86-21-58550039;86-21-31268550-8004

Address:Suite B-10#, 6999 Chuansha Road, Pudong District, Shanghai 201202, China
HANGZHOU ICH BIOFARM CO.,LTD

Contact:+86-571-28186845

Address:Room 1224,Eastcom Mansion,398 Wensan Road,Hangzhou,310013 China
Jiangsu Taihu New Materials Holding Co., Ltd

Contact:+86-519-86160108

Address:Xueyan Town, Changzhou City, Jiangsu Province, 213169, China

Relevant to this article

Hydroselenation and carboselenation of electron-deficient alkynes with isolable (Hydrido)(selenolato)platinum(II) complexes and a selenaplatinacycle bearing a triptycene skeleton

Doi:10.1002/ejoc.200901408
(2010)
Synthesis and in vitro antiprotozoal activities of 5-phenyliminobenzo[a] phenoxazine derivatives

Doi:10.1016/j.bmcl.2011.07.112
(2011)
Synthesis of α,ω-Diamino Acids via Amidocarbonylation Reaction: Novel Synthesis of Lysine, Ornithine, and Their Analogs

Doi:10.1246/bcsj.64.613
(1991)
Behavior of neutral phosphido derivatives of platinum and palladium toward silver centers

Doi:10.1021/ic201354s
(2011)
A Modular Synthesis of 4-Aminoquinolines and [1,3] N-to-C Rearrangement to Quinolin-4-ylmethanesulfonamides

Doi:10.1021/acs.orglett.7b01701
(2017)
Further studies on the dialkylation chemistry of [Pt₂(μ-S) ₂(PPh₃)₄] with activated alkyl halides RC(O)CH₂X (X = Cl, Br)

Doi:10.1016/j.ica.2011.06.023
(2011)

Article Doi