A NOVEL, DOUBLE-ASYMMETRIC ALDOL APPROACH TO THE SYNTHESIS OF A 1β-METHYL CARBAPENEM ANTIBIOTIC PRECURSOR

DOI: 10.1016/S0040-4039(00)82373-4

Source and publish data:

Tetrahedron Letters p. 6461 - 6464 (1988)

Update date:2022-08-03

Topics:

Authors:

Shirai, Fumiyuki

Nakai, Takeshi

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Article abstract of DOI:10.1016/S0040-4039(00)82373-4

A novel synthetic approach to the 1β-methyl carbapenem key precursor is described which involves the chelation-controlled double-asymmetric aldol reaction as the key step.

Full text of DOI:10.1016/S0040-4039(00)82373-4

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