DIETHOXYMETHYLPHOSPHONITES AND PHOSPHINATES. INTERMEDIATES FOR THE SYNTHESIS OF α,β- AND γ-AMINOALKYLPHOSPHONOUS ACIDS

Article abstract of DOI:10.1016/S0040-4020(01)89240-1

New building blocks for the synthesis of functional alkyl phosphonous acids are described.Diethoxymethylphosphonites and phosphinates are readily prepared and undergo reactions typical of phosphites and phosphonates.The products are stable to chemical transformations, readily handled and purified, and easily transformed to the phosphonous acids.