
Journal of Organic Chemistry p. 1423 - 1424 (1990)
Update date:2022-08-04
Topics:
Ireland, Robert E.
Wipf, Peter
Miltz, Wolfgang
Vanasse, Benoit
The enantioselective synthesis of the spiroenones 3, 4 from (S)-glycidol-O-benzyl ether and lithiated furan derivatives is described.After conjugate addition of lithium dimethyl cuprate or lithium divinyl cuprate and conversion of the resulting saturated ketones to their respective iodides 7 and 8, fragmentation of these halides leads to the formation of acyclic aldol-containing carbon skeletons.
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