Bicyclic β-sultams: Synthesis from monocyclic β-aminothiols and some properties

Article abstract of DOI:10.1002/ardp.19903230208

The cyclamine methanethiols 7 are prepared from the corresponding alcohols 3 and oxidatively transformed by treatment with chlorine into the cyclic substituted taurinechlorides 8. Upon treatment with bases, 8 is cyclized yielding the bicyclic β-sultams 9. Some spectroscopic properties and the solvolysis of 9 are briefly discussed.