Donor substituted 2,5-dihydropyrazines as dienophiles in the Diels-Alder-reaction with inverse electron demand. A simple synthesis of substituted pyrazino[2,3-d]pyridazines

Article abstract of DOI:10.1002/ardp.19903230207

The title reaction, starting with various donor substituted 2,5-dihydropyrazines such as 7 and 12-14 as electron rich dienophiles, results in the formation of the novel pyrazino[2,3-d]pyridazines 9 and 15-17 in good yields.