Chirality transfer from lactic acid selective synthesis of 2,2-disubstituted-1,3-dioxolan-4-ones from ketones and acetals

Article abstract of DOI:10.1016/0040-4039(90)80091-Y

Diastereomeric 2,2-disubstituted-5-methyl-1,3-dioxolan-4-ones were prepared from lactic acid and ketones or their acetals with excellent control of stereochemistry under kinetic or thermodynamic reaction conditions.