Synthesis of Furo[2,3-c]pyran-β-D-nucleosides by radical-cyclization and their conformational analysis by 500 MHz 1H-NMR spectroscopy

Article abstract of DOI:10.1016/S0040-4020(01)91032-4

Free-radical, generated from the 3'-phenylseleno nucleosides as the radical precursors 2-5, was efficiently trapped intramolecularly by an olefin or alkyne function anchored from the 5'-end by an ether function to give various [3.4.0]-cis-fused furo[2,3-c