Solid phase synthesis of a model nucleopeptide with a phosphodiester bond between the 5′ end of a trinucleotide and a serine residue

DOI: 10.1016/S0040-4039(00)92178-6

Source and publish data:

Tetrahedron Letters p. 4389 - 4392 (1991)

Update date:2022-09-26

Topics:

Authors:

Robles, Jordi

Pedroso, Enrique

Grandas, Anna

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Article abstract of DOI:10.1016/S0040-4039(00)92178-6

The model nucleopeptide Boc-Ser(pTCT)-NHcHex has been assmbled on a polystyrene solid support using the phosphite triester approach. Fmoc and cyanoethyl groups have been used to protect the exocyclic amine of cytosine and phosphate groups respectively. Fi

Full text of DOI:10.1016/S0040-4039(00)92178-6

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