Differential binding energy: A detailed evaluation of the influence of hydrogen-bonding and hydrophobic groups on the inhibition of thermolysin by phosphorus-containing inhibitors

DOI: 10.1021/ja00001a043

Source and publish data:

Journal of the American Chemical Society p. 297 - 307 (1991)

Update date:2022-08-03

Topics:

Authors:

Morgan, Bradley P.

Scholtz, John M.

Ballinger, Marcus D.

Zipkin, Ilan D.

Bartlett, Paul A.

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Article abstract of DOI:10.1021/ja00001a043

Two series of phosphorus-containing peptide analogues, 3 (CbZ-Gly-ψ(PO₂^-CH₂)Leu-Xaa) and 4 (Cbz-Gly-ψ-(PO₂^-NH)Leuψ[CO₂]Xaa), have been synthesized and evaluated as inhibitors of the zinc en

Full text of DOI:10.1021/ja00001a043

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