Non-Electron-Transfer Quinone-Mediated Oxidative Cleavage of Cyclopropylamines. Implications Regarding Their Utility as Probes of Enzyme Mechanism

DOI: 10.1021/jo00004a004

Source and publish data:

Journal of Organic Chemistry p. 1353 - 1355 (1991)

Update date:2022-08-05

Topics:

Authors:

Sayre, Lawrence M.

Singh, Malvinder P.

Kokil, Pandurang B.

Wang, Fengjiang

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Article abstract of DOI:10.1021/jo00004a004

3,5-Di-tert-butyl-1,2-benzoquinone effects oxidative cleavage of cylopropylamine (CPA) and its 1-phenyl analogue via o-quinoneimine intermediates, a reaction which may serve as a model for the inactivation of plasma amine oxidase by CPA.

Full text of DOI:10.1021/jo00004a004

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