Metalation and electrophilic quenching of C-4 functionalized isoxazoles; VIII. Preparation of derivatives of 5-thioalkylisooxazoles

Article abstract of DOI:10.1055/s-1990-27099

The lateral metalation and electrophilic quenching of isoxazoles bearing electron withdrawing groups in the 4-position 1 with disulfides, represents a selective, direct and synthetically useful entry to the thioalkyl derivatives 2 (nine examples). One exc