Binding of Substituted and Conformationally Restricted Derivatives of N-(3-Phenyl-n-propyl)-1-phenyl-2-aminopropane at ?-Receptors

Article abstract of DOI:10.1021/jm00110a015

Certain benzomorphans, such as N-allylnormetazocine, are classical "?-opiates" that bind both at ? and phencyclidine (PCP) binding sites with modest affinity.Recently, we identified N-substituted 2-phenylaminoethane as being the primary ?-pharmacophore of