The synthesis of pyrano[3,2-e]indoles and pyrano[2,3-f]indoles as rotationally restricted phenolic analogs of the neurotransmitter serotonin

Article abstract of DOI:10.1016/S0040-4020(01)88200-4

The synthesis of two rotationally restricted phenolic analogs (1a and 1b) of the neurotransmitter serotonin have been accomplished. The syntheses of 8,9-dihydropyrano[3,2-e]indole (13a) and 7,8-dihydropyrano[2,3-f]indole (13b), which formed the template f