Diels-Alder Reactions of Vinylindoles with Aryne and 1,4-Benzoquinones: New Potential DNA Intercalators

DOI: 10.1007/BF00810830

Source and publish data:

Monatshefte fur Chemie p. 291 - 298 (1991)

Update date:2022-08-04

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Authors:

Pindur, Ulf

Pfeuffer, Ludwig

Eitel, Manfred

Rogge, Martina

Haber, Manfred

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Article abstract of DOI:10.1007/BF00810830

Diels-Alder reactions of 2- and 3-vinylindoles with aryne, 1,4-benzo- and 1,4-naphthoquinone lead to new six-ring annellated carbazoles.Molecular modeling studies predict that the compounds with coplanar framework are able to intercalate with the B-DNA.

Full text of DOI:10.1007/BF00810830

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