Journal of Fluorine Chemistry p. 381 - 396 (1991)
Update date:2022-07-29
Topics:
Leeper, Finian J.
Rock, Martin
5-Amino-2-fluorolaevulinic acid 3 has been synthesized in high yield by modification of a new route to 5-aminolaevulinic acid (ALA), involving γ-lactone intermediates.Initial studies suggest that 3 is an inhibitor of ALA dehydratase, an early enzyme of tetrapyrrole biosynthesis.
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