HIGHLY STEREOSELECTIVE AND GENERAL SYNTHESIS OF (Z)-3-METHYL-2-ALKEN-1-OLS VIA PALLADIUM-CATALYZED CROSS COUPLING OF (Z)-3-IODO-2-BUTEN-1-OL WITH ORGANOZINCS AND OTHER ORGANOMETALS

DOI: 10.1016/S0040-4039(00)60312-X

Source and publish data:

Tetrahedron Letters p. 1437 - 1440 (1993)

Update date:2022-08-04

Topics:

Authors:

Negishi, Ei-ichi

Ay, Mehmet

Gulevich, Yuri V.

Noda, Yumiki

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)60312-X

The reaction of Zn-protected (Z)-3-iodo-2-buten-1-ol with organozincs in the presence of 1-5 mol percent of a Pd complex, e.g., Pd(PPh3)4 or Cl2Pd(PPh3)2 and n-BuLi (2 equiv), in DMF provides a highly stereoselective (>/= 96 percent), general, and high-yi

Full text of DOI:10.1016/S0040-4039(00)60312-X

Products guided by the article

Product name:(Z)-3-Methyl-5-(2,6,6-trimethyl-cyclohex-1-enyl)-pent-2-en-4-yn-1-ol

Cas No:137047-34-8

R&D Labs maybe for 137047-34-8

Zhejiang kehong chemical co., ltd

Contact:0086-575-85522000

Address:xiner center RD binhai industrial zone shaoxing zhejiang province P.R.China,312073
Changsha Huajing Powdery Material Technological Co., Ltd.

Contact:86-731-88879686

Address:Building 2, West Garden, Main Campus of Central South University, Changsha, Hunan Province, China
Jiangxi Huashi Pharmaceutical Co., Ltd

Contact:+86-795-4509628

Address:Ningbo Ave., Fengtian Industrial Park, Fengxin Country, Jiangxi, China.
Du-Hope International Group

website:http://www.np-chem.com

Contact:0086-25-52346877

Address:199, Jian Ye Road, Nanjing, China
Shuanghe Bio-Technology Limited(expird)

Contact:+86-571-61710758,18968016640

Address:Jinqiao north road 916# Fuyang

Relevant to this article

First Lewis acid catalyzed generation and reaction of α- organylsulfanyl and α-organylselanyl carbenium ions using ethyl α-fluoroacetate derivatives

Doi:10.1002/ejoc.200500179
(2005)
Doi:10.1002/jlcr.2580120204
(1976)
Novel hole transport materials based on triarylamine/naphtho[2,1-b]benzofunan for efficient green electroluminescent device

Doi:10.1016/j.tet.2017.06.031
(2017)
Imidazol(in)ium hydrogen carbonates as a genuine source of N-heterocyclic carbenes (NHCs): Applications to the facile preparation of NHC metal complexes and to NHC-organocatalyzed molecular and macromolecular syntheses

Doi:10.1021/ja3005804
(2012)
Synthesis and optimization of furano[3,2-d]pyrimidines as selective spleen tyrosine kinase (Syk) inhibitors

Doi:10.1016/j.bmcl.2016.09.077
(2016)
Selective saccharide recognition using modular diboronic acid fluorescent sensors

Doi:10.1002/ejoc.201101633
(2012)

Article Doi