N,N-diisopropyl-O-P-nitrophenyl-P-methylphosphonoamidite: Novel difunctional PIII reagent in oligonucleoside methylphosphonate synthesis containing 4-nitrophenoxy group

Article abstract of DOI:10.1016/S0040-4039(00)93513-5

First example of the P^III coupling reagent containing 4-nitrophenoxy group is described. Its usefulness is demonstrated by synthesis of dinucleoside methylphosphonate and methylthiophosphonate.