Synthesis and β-adrenergic activity of atypical β-adrenergic phenylethanolaminotetralin stereoisomers

Article abstract of DOI:10.1016/0223-5234(94)90095-7

A series of substituted phenylethanolaminotetralins were synthesized as pure stereoisomers and their ability to stimulate atypical β-adrenoceptors selectively was evaluated.The compounds in vitro relative potencies were assessed using the atypical β respo