Synthesis and biological evaluation of 2-[substituted acetyl]amino-5-alkyl-1,3,4-thiadiazoles

Article abstract of DOI:10.1016/0223-5234(92)90063-7

Some new N-substituted acetyl derivatives of 2-amino-5-alkyl-1,3,4-thiadiazoles have been prepared and investigated for antihistaminic and spasmolytic activity on guinea pig ileum. A few of the compounds showed encouraging effects. In addition, some of th