EFFICIENT OPTICAL RESOLUTION OF SOME KEY COMPOUNDS OF PROSTAGLANDIN SYNTHESIS

Article abstract of DOI:10.1016/S0957-4166(00)80255-4

4-Hydroxycyclo-2-pentenone (1a), 2-allyl-4-hydroxycyclo-2-pentenone (2), bicyclo<3.2.0.>-2-hepten-6-one (4), and bicyclo<4.2.0>-2-octen-7-one (6) were resolved efficiently by complexation with optically active host compound (3).Preparation of a new host compound (3b) was also described.