Highly enantiospecific platinum-catalyzed cycloisomerizations: Synthesis of enantioenriched oxabicycloheptene derivatives

Article abstract of DOI:10.1021/ol400625f

Enantiospecific cycloisomerizations of 1,6-enynes to form oxabicyclo[4.1.0]heptene derivatives are described. Enantiospecificity is consistently high regardless of alkene or alkyne substitution, providing a general approach to greatly enantioenriched cycl