Synthesis of Pyrimidines from 2-Trichloromethyl-4-dimethylamino-1,3-diaza-1,3-butadienes and Electron Deficient Acetylenes

DOI: 10.1016/S0040-4039(00)92660-1

Source and publish data:

Tetrahedron Letters p. 3449 - 3452 (1992)

Update date:2022-08-03

Topics:

Authors:

Guzman, Angel

Romero, Moises

Talamas, Francisco X.

Muchowski, Joseph M.

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Article abstract of DOI:10.1016/S0040-4039(00)92660-1

2-Trichloromethyl-4-dimethylamino-1,3-diaza-1,3-butadienes(3), prepared from trichloroacetamidine(1) and amide acetals 2, readily react with electron deficient acetylenes 4 to give 2-trichloromethylpyrimidines 5.

Full text of DOI:10.1016/S0040-4039(00)92660-1

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Product name:ethyl 2-(trichloromethyl)-4-phenylpyrimidine-5-carboxylate

Cas No:143034-49-5

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