A simple synthesis of 4,5-dihydro-5H-1,3,4-benzoxadiazepin-5-ones

Article abstract of DOI:10.1055/s-1992-26264

A simple method for the synthesis of 4,5-dihydro-5H-1,3,4-benzoxadiazepin-5-ones 4 based on the reaction of salicyclic hydrazide (1) with one carbon insertion units, such as carboxylic acid anhydrides, acid chlorides, and ortho esters is reported.