Bioorganic and Medicinal Chemistry Letters p. 497 - 500 (1999)
Update date:2022-08-02
Topics:
Abell, Andrew D.
Oldham, Mark D.
The four stereoisomers of 3-(N-acetylleucylamino)-3-benzyl-1- [(methylsulfonyl)oxy]succinimide have been prepared and shown to inhibit α- chymotrypsin and human neutrophil elastase. The structural and stereochemical features that affect the potency and selectivity of inhibition are discussed.
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