Archiv der Pharmazie p. 727 - 732 (1992)
Update date:2022-07-31
Topics:
Neidlein
Strein
Pressmar
Kramer
Michel
The 13C- and 14C-labelled derivatives of the vasodilating nitric acid ester trans-2-amino-2-methyl-N-(4-nitroxycyclohexyl)-propionamide (BM 12.1179) (1) have been synthesized starting from the sterically hindered α-amino-isobutyric acid (2) via the oxazolone (synthesis of 13C-BM 12.1179) and the acid chloride (synthesis of 14C-BM 12.1179). Various amine-protecting groups and methods for activating the carboxy-function are compared.
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Doi:10.1016/j.jorganchem.2004.10.005
(2005)Doi:10.3906/kim-1211-36
(2013)Doi:10.1016/0022-328X(92)85080-G
(1992)Doi:10.1016/j.tet.2009.11.050
(2010)Doi:10.1039/c3ra42569j
(2013)Doi:10.1016/S0040-4039(00)60841-9
(1992)
