Journal of Medicinal Chemistry p. 2887 - 2892 (1995)
Update date:2022-08-03
Topics:
Kumazawa, Toshiaki
Takami, Hitoshi
Kishibayashi, Nobuyuki
Ishii, Akio
Nagahara, Yoshitomo
et al.
A series of (E)-4-<2-<<3-(indol-5-yl)-1-oxo-2-butenyl>amino>phenoxy>butyric acid derivatives was prepared, and the derivatives were demonstrated to be potent inhibitors of steroid 5α-reductase in the rat prostate.The structure - activity relationships wer
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