Heterocycles p. 2301 - 2311 (1992)
Update date:2022-08-04
Topics:
Jacquet, Jean-Pierre
Bouzard, Daniel
Cesare, Pierre Di
Dolnic, Nicolas
Massoudi, Massoud
Remuzon, Philippe
A series of 5-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acids was prepared in which the N-1 position was substituted by various aryl groups.Seven compounds showed excellent in vitro antibacterial activity against Gram-positive and Gram-negative strains.
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