3-Aryl-2-(3'-substituted-1',2',4'-oxadiazol-5'-yl)tropane analogues of cocaine: Affinities at the cocaine binding site at the dopamine, serotonin, and norepinephrine transporters

DOI: 10.1021/jm00072a007

Source and publish data:

Journal of Medicinal Chemistry p. 2886 - 2890 (1993)

Update date:2022-09-26

Topics:

Authors:

Carroll Carroll

Gray Gray

Abraham Abraham

Kuzemko Kuzemko

Lewin Lewin

Boja Boja

Kuhar Kuhar

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Article abstract of DOI:10.1021/jm00072a007

Previous studies have shown that 3β-(substituted phenyl)tropan-2β- carboxylic acid esters possess high affinity for the cocaine binding site on the dopamine transporter both in vitro and in vivo and inhibit dopamine uptake in vitro. Since 1,2,4-oxadiazole

Full text of DOI:10.1021/jm00072a007

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