A new synthesis of 24-fluoro-1α,25-dihydroxyvitamin D2 and its 24-epimer, and determination of the C-24 configuration

DOI: 10.1248/cpb.40.2932

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 2932 - 2936 (1992)

Update date:2022-08-02

Topics:

Authors:

Hayashi Hayashi

Ojima Ojima

Konno Konno

Manaka Manaka

Yamaguchi

Yamada Yamada

Takayama

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.40.2932

A new synthesis of 24-fluoro-1α,25-dihydroxyvitamin D₂ (4a) and its 24-epimer (4b) is described. Starting with 1α,3β-bis[(tert-butyldimethylsilyl)oxy]-24-norchol-5,7-dien-23-al (5), a mixture of 4a and 4b was obtained in 3% overall yield in 6 s

Full text of DOI:10.1248/cpb.40.2932

NII-Electronic Library Service

Products guided by the article

Product name:(22E,24R)-1α,3β-bis<(tert-butyldimethylsilyl)oxy>-5α,8α-(3,5-dioxo-4-phenyl-1,2,4-triazolidin-1,2-diyl)-24-fluoro-6,22-ergostadien-25-ol

Cas No:147200-39-3

R&D Labs maybe for 147200-39-3

LIAOYANG WANRONG CHEMICALS COMPANY LIMITED

Contact:86-419-2390789

Address:XINLI VILLAGE , DONG NINGWEI COUNTY,TAIZIHE DISTRICT, LIAOYANG , LIAONING
Xiamen Goodhealth Pharmchem Co., Ltd.

Contact:0086-592-2097683

Address:404R No.2 54# Minzu Rd., Xiamen, China
Xinchang Yueding Chemical Co., Ltd.

Contact:86-571-56926323

Address:NO.90 BEIMENCHENGWAI CHENGGUAN TOWN XINCHANG
Antaeus Bio-technology Co., LTD(expird)

Contact:021-31252569

Address:shanghai pudong
Taixing Joxin Bio-tec Co.,Ltd.

website:http://www.joxbio.com

Contact:86-523-87558858 87612088

Address:No.88, chengdong industrial park

Relevant to this article

Doi:10.1021/jm00315a044
(1967)
Direct introduction of CH₂OH by intermolecular trapping of CO

Doi:10.1016/S0040-4039(00)61627-1
(1992)
Total synthesis of natural (-)-ptaquilosin, the aglycon of a potent bracken carcinogen ptaquiloside, and the (+)-enantiomer and their DNA cleaving activities

Doi:10.1021/ja00061a003
(1993)
Azacalixarenes: New Macrocycles with Dimethyleneaza-Bridged Calix<4>arene Systems

Doi:10.1021/jo00063a042
(1993)
A cascade cross-coupling hydrogen evolution reaction by visible light catalysis

Doi:10.1021/ja408486v
(2013)
Synthesis, X-ray structure, electrochemical properties and cytotoxic effects of new arene ruthenium(II) complexes

Doi:10.1016/j.jorganchem.2013.07.020
(2013)

Article Doi