Tandem nucleophilic reaction leading to hydrofurans: Application to one- pot synthesis of antitumor naphthofuran natural product

DOI: 10.3987/COM-98-8430

Source and publish data:

Heterocycles p. 497 - 500 (1999)

Update date:2022-08-03

Topics:

Authors:

Hagiwara, Hisahiro

Sato, Kouji

Suzuki, Toshio

Ando, Masayoshi

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.3987/COM-98-8430

The reaction of enolates of 1,3-dicarbonyl compounds (1) with 3,4- dibromo-2-butanone (2) afforded hydrofuran derivatives (4) or (5) in the presence of DBU in THF and the reaction was applied to the one-pot synthesis of antitumor naphthofuran products (29).

Full text of DOI:10.3987/COM-98-8430

Products guided by the article

Product name:Naphtho[2,3-b]furan-4,9-dione, 2-acetyl-2,3-dihydro-

Cas No:147568-55-6

R&D Labs maybe for 147568-55-6

GIHI CHEMICALS CO.,LIMITED

Contact:+86-571-86217390

Address:No.567 Dengcai Street,Sandun,Westlake District,Hangzhou310030,Zhejiang,China.
KAIYUAN CHEMICAL COMPANY LIMITED.

website:http://www.kaiyuanchem.com

Contact:+86-22-59891255/66/77

Address:B-2205, Kuangshi International Building, Yingbin Road, XiangLuo Bay Business District, Binhai New area, Tianjin, China.
Sinoway Industrial Co., Ltd.

website:http://www.china-sinoway.com

Contact:+86-592-5853819

Address:16/F,Huicheng Comm,Complex,No839 XiaHe Rd, Xiamen,China
Li's chemicals

Contact:+86-15850770348

Address:51 OF XIANGFANGCUN ROAD, Nanjing 210002, China
JIAXING SUNS INTERNATIONAL TRADE CO LTD

Contact:18367306858

Address:No.123,Huixin Avenue,Huimin Dist

Relevant to this article

Stereocontrolled syntheses of C-linked deoxyribosides of 2-hydroxypyridine and 2-hydroxyquinoline

Doi:10.1016/S0040-4039(00)92690-X
(1991)
Doi:10.1021/jo00832a038
(1970)
Benzomorphan analogues with doxpicomin substructure: Synthesis and psychopharmacological investigation of 5-aminomethyl and 5-(α-aminobenzyl) substituted 2,6-epoxy-3-benzoxocines

Doi:10.1002/ardp.19933260311
(1993)
Synthesis and characterization of the dihydrosalpren ligand (H₂L¹) and of its trinuclear Ni(II) complex

Doi:10.1016/j.inoche.2009.05.003
(2009)
Regioselective β-Addition of Sulfonyl Anions to an α,β-Epoxysilane. Use of Triphenylsilyloxirane for Synthesis of Stable Cyclopropene Derivatives

Doi:10.1039/c39920000802
(1992)
Heterocyclic Transformations. Part 5: Studies in Reactions of 6-Methyl-1,3-oxazine-2,4(3H)-dione with Arylamines - a Facile Synthesis of 1-Aryl-6-methyluracils

Doi:10.1039/P19930000731
(1993)

Article Doi