Enantioconvergent Synthesis of a Promising HMG Co-A Reductase Inhibitor NK-104 from Both Enantiomers of Epichlorohydrin

DOI: 10.1016/S0957-4166(00)82337-X

Source and publish data:

Tetrahedron Asymmetry p. 201 - 204 (1993)

Update date:2022-08-05

Topics:

Authors:

Takano, Seiichi

Kamikubo, Takashi

Sugihara, Takumichi

Suzuki, Mikio

Ogasawara, Kunio

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0957-4166(00)82337-X

An enantioconvergent synthesis of (+)-NK-104 (3), a promising HMG Co-A reductase inhibitor, has been developed from both enantiomers of epichlorohydrin.

Full text of DOI:10.1016/S0957-4166(00)82337-X

Products guided by the article

Product name:2-Cyclopropyl-4-(4-fluoro-phenyl)-3-phenylsulfanylmethyl-quinoline

Cas No:148516-12-5

R&D Labs maybe for 148516-12-5

Beijing Mesochem Technology Co.,LTD

website:http://www.mesochem.com

Contact:0086-10-57862036

Address:2301, Floor 23, Building 9 Lippo Plaza, Yard 8 Ronghua Middle Road, ETDZ, Beijing, China
Zhejiang Quzhou Jiancheng Silicone Co., Ltd.(Shanghai Jiancheng Industial and Trade Co, Ltd)

Contact:18957018777 +86-570-3888777

Address:The company production base address： Quzhou City, Zhejiang Province high-tech industrial park Nianhua Road 37
Dezhou Longteng Chemical Co., Ltd.

website:http://www.sodium-methoxide.cn/

Contact:0086-18866052283

Address:Xinhua Industrial Zone, Dezhou City, Shandong Province, China
Hangzhou LINGEBA Technology Co., Ltd.

Contact:+0086-571-87389059

Address:Office 1-913,NewYouth Plaza, GongShu Area, HangZhou,ZheJiang,P.R.China
Shanghai birch chemical technology co.,ltd

Contact:+86-21-54096810

Address:No.2588,Jungong Road,Shanghai,China

Relevant to this article

INTRAMOLECULAR EXCHANGE IN TERTIARY PHOSPHINE DERIVATIVES OF DODECACARBONYLTRIOSMIUM

Doi:10.1016/0022-328X(85)87133-3
(1985)
Photoamination of 2-Alkoxynaphthalenes with Alkylamines via Electron Transfer and Its Application to Synthesis of 1-Alkylamino-2-tetralones

Doi:10.1246/bcsj.67.246
(1994)
Hemisynthesis and structural and chromatic characterization of delphinidin 3- O -glucoside-vescalagin hybrid pigments

Doi:10.1021/jf4033188
(2013)
Pyrazole-based cathepsin S inhibitors with improved cellular potency

Doi:10.1016/j.bmcl.2007.08.038
(2007)
Catalytic Enantioselective Aza-pinacol Rearrangement

Doi:10.1002/anie.201705539
(2017)
Synthesis and photochemical behaviour of 4-nitroimidazoles in the presence of oxygen

Doi:10.1016/S0040-4020(01)90240-6
(1993)

Article Doi