Histamine analogues, XXXV: 2-Substituted histamine derivatives containing classical moieties of H2-antagonists - A novel class of H1-agonists

Article abstract of DOI:10.1002/ardp.19933260306

A new type of H₁-agonists resulted from the combination of the essential histamine structure with parts of H₂-antagonists. 2,4-Disubstituted imidazole derivatives were synthesized by reaction of imidic acid methyl esters with 1,3-dih