Structure-activity relationship of a series of phenylureas linked to 4- phenylimidazole. Novel potent inhibitors of acyl-CoA:cholesterol O- acyltransferase with antiatherosclerotic activity. 2

DOI: 10.1021/jm00063a014

Source and publish data:

Journal of Medicinal Chemistry p. 1641 - 1653 (1993)

Update date:2022-07-30

Topics:

Authors:

Kimura Kimura

Watanabe

Matsui Matsui

Hayashi Hayashi

Tanaka Tanaka

Ohtsuka Ohtsuka

Saeki Saeki

Kogushi Kogushi

Kabayashi

Akasaka Akasaka

Yamagishi

Saitou Saitou

Yamatsu Yamatsu

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00063a014

In our continuing search to find systemically bioavailable ACAT (acyl- CoA:cholesterol O-acyl-transferase) inhibitors with more potent antiatherosclerotic effect than N-[2-(dimethylamino)-6-[3-(5-methyl-4- phenyl-1H-imidazol-1-yl)propoxy]phenyl]-N'-pentyl

Full text of DOI:10.1021/jm00063a014

Products guided by the article

Product name:3-methyl-2-nitro-N-<2-(5-methyl-4-phenyl-1H-imidazol-1-yl)ethyl>benzamide

Cas No:149376-44-3

R&D Labs maybe for 149376-44-3

Radiant Pharma & Tech Company

Contact:+86-511-88790000

Address:338 North Yushan Rd, Zhenjiang, Jiangsu 212016
Changzhou Hopschain Chemical Co.,Ltd

website:http://www.hopschem.cn/products.html

Contact:86-519-85528066

Address:Room 710, Unit A, Xingbei Development Mansion, Tongjiang Road, Changzhou City,213000, China
Sanming Coffer Fine Chemical Industrial Co., Ltd

website:http://www.cofferxm.com/

Contact:+86-598-5853979

Address:Jin-sha Yuan Chuang-ye Park,Hi-Tech Development Zone,Sanming City P.R.China
Nantong LiKai Chemical Co.,Ltd

Contact:+86-513-89068669

Address:Jincheng Science Park
Alway Chem, China

website:http://www.alwaychem.com

Contact:+86-532-8586-4000, 8586-5000

Address:NO.51, TAIPING ROAD, QINGDAO, CHINA. 266001

Relevant to this article

Azulene derivatives as TXA₂/PGH₂ receptor antagonists - II. Synthesis and biological activity of 6-mono- and 6-dihydroxylated-isopropylazulenes

Doi:10.1016/0968-0896(96)00038-7
(1996)
Studies on Neurokinin Antagonists. 3. Design and Structure-Activity Relationships of New Branched Tripeptides N^α-(Substituted L-aspartyl, L-ornithyl, or L-lysyl)-N-methyl-N-(phenylmethyl)-L-phenylalaninamides as Substance P Antagonists

Doi:10.1021/jm00068a003
(1993)
A divergent approach to the total synthesis of the marine pyridoacridine alkaloid eilatin and its synthetic isomer isoeilatin

Doi:10.1016/j.tetlet.2015.01.176
(2015)
Selective C-H fluorination of pyridines and diazines inspired by a classic amination reaction

Doi:10.1126/science.1243759
(2013)
Bakers' yeast oxidation of methyl para-tolylsulfide: Synthesis of a chiral intermediate in the preparation of the mevinic acid-type hypocholestemic agents

Doi:10.1016/0040-4020(95)00819-T
(1995)
Neutral and ionic cycloruthenated 2-phenylindoles as cytotoxic agents

Doi:10.1021/om400941b
(2013)

Article Doi