
Journal of the American Chemical Society p. 3367 - 3374 (1994)
Update date:2022-08-05
Topics: Total synthesis
Paquette, Leo A.
Wang, Ting-Zhong
Philippo, Christophe M. G.
Wang, Shaopeng
The total synthesis of (+)-cleomeolide (1) has been accomplished. The key construction elements of this cembranoid lactone were (i) improved conversion of optically pure Wieland-Miescher ketone into dienol ether 12 and oxidative cleavage of the latter to
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