Synthesis of oligonucleotides containing N2-2-(imidazol-4-ylacetamido)ethyll-2′-deoxyguanosine

Article abstract of DOI:10.1016/S0040-4039(00)61685-4

Synthesis of 2′-deoxyguanosine tethered through N-2 to an imidazole is described. The modified 2′-deoxyguanosine was converted to two different phosphoramidites, one with and the other without a 6-O-protecting group. The phosphoramidites were incorporated