Oligodeoxynucleotide analogues containing 3'-deoxy-3'-C-threo-hydroxymethylthymidine: Synthesis, hybridization properties and enzymatic stability

DOI: 10.1016/S0040-4020(01)81816-0

Source and publish data:

Tetrahedron p. 11341 - 11352 (1993)

Update date:2022-08-03

Topics:

Authors:

Svendsen

Wengel Wengel

Dahl Dahl

Kirpekar

Roepstorff

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Article abstract of DOI:10.1016/S0040-4020(01)81816-0

Novel oligodeoxynucleotide analogues containing 3'-C-threo-methylene phosphodiester internucleoside linkages were synthesized on automated DNA-synthesizers using the phosphoramidine approach. The sugar modified phosphoramidite building block 5 was obtaine

Full text of DOI:10.1016/S0040-4020(01)81816-0

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Product name:1-(2,3-dideoxy-5-O-(4,4'-dimethoxytrityl)-3-C-hydroxymethyl-β-D-threo-pentofuranosyl)thymine

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