Oligodeoxynucleotide analogues containing 3'-deoxy-3'-C-threo-hydroxymethylthymidine: Synthesis, hybridization properties and enzymatic stability

DOI: 10.1016/S0040-4020(01)81816-0

Source and publish data:

Tetrahedron p. 11341 - 11352 (1993)

Update date:2022-08-03

Topics:

Authors:

Svendsen

Wengel Wengel

Dahl Dahl

Kirpekar

Roepstorff

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4020(01)81816-0

Novel oligodeoxynucleotide analogues containing 3'-C-threo-methylene phosphodiester internucleoside linkages were synthesized on automated DNA-synthesizers using the phosphoramidine approach. The sugar modified phosphoramidite building block 5 was obtaine

Full text of DOI:10.1016/S0040-4020(01)81816-0

Products guided by the article

Product name:1-(2,3-dideoxy-5-O-(4,4'-dimethoxytrityl)-3-C-hydroxymethyl-β-D-threo-pentofuranosyl)thymine

Cas No:154371-09-2

R&D Labs maybe for 154371-09-2

Chameleon Specialty Chemicals

Contact:+44 7958 511245

Address:PO Box 469, Manchester, UK
KindChem Co.,Ltd,

Contact:+86-25-85281586

Address:13F,Bld2#,South of Longpan Road
Changde Yungang Biotechnology Co., Ltd

website:http://www.cdyg.com

Contact:+86-736-7391178

Address:Qiaonan Industrial Park, Changde City, Hunan Province
Shanghai Egoal Chemical Co.,Ltd

Contact:+86-21-50333091

Address:Yangming Garden Square 3,YangGao North Road 1188, Pudong New District, Shanghai
Hangzhou Dingyan Chem Co., Ltd

website:http://www.dingyanchem.com

Contact:86-571-87157530

Address:RM.1118,NO.1 Building, Baiyun Tower,Jianggan Area, Hangzhou city, China,310004

Relevant to this article

Synthesis and antitumor activity of a series of [2-substituted-4,5- bis(aminomethyl)-1,3-dioxolane]platinum(II) complexes

Doi:10.1021/jm00036a013
(1994)
Doi:10.1016/0020-1693(93)03730-X
(1994)
A novel and versatile silicon-derived linkage agent, 4-[1-hydroxy-2-(trimethylsilyl)ethyl]benzoic acid, compatible with the Fmoc/t-Bu strategy for solid-phase synthesis of C-terminal peptide acids

Doi:10.1021/ja00084a016
(1994)
Doi:10.1021/jo01056a039
(1962)
Mild protocols for generating molecular complexity: A comparative study of hetero-domino reactions based on the oxidant and the substitution pattern

Doi:10.1002/ejoc.200400549
(2005)
(E)-5-(3-oxopropen-1-yl)-2'-deoxyuridine and (E)-5-(3-oxopropen-1-yl)-2',3'-dideoxyuridine; new antiviral agents: Syntheses and biological activity

Doi:10.1016/0040-4039(94)88009-3
(1994)

Article Doi