Aryl radical cyclisation approach to highly substituted oxindoles related to mitomycins

DOI: 10.1016/S0040-4039(00)61569-1

Source and publish data:

Tetrahedron Letters p. 7797 - 7798 (1993)

Update date:2022-07-29

Topics:

Authors:

Jones Jones

Storey Storey

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Article abstract of DOI:10.1016/S0040-4039(00)61569-1

Radical cyclisation of the hexa-substituted aromatic compounds 8 and 17 leads to highly substituted oxindoles 9 and 18 respectively in excellent yields. Oxindole 18 carries the correct substitution pattern for ring-A of mitomycin A.

Full text of DOI:10.1016/S0040-4039(00)61569-1

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