
Tetrahedron p. 3123 - 3138 (1994)
Update date:2022-07-29
Topics:
Schlag, Wolf-Ruediger
Vilsmaier, Elmar
Maas, Gerhard
6-Piperidino-3-azabicyclo<3.1.0>hexane-6-carboxamide diastereomers 5 and 7 represent conformationally rigid analogues of the pharmacophoric group 1.Compounds 5 and 7 were synthesized with high stereoselectivity via chloroenamines 12a and 13b, respectively
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(1966)