
Tetrahedron Asymmetry p. 2251 - 2254 (1994)
Update date:2022-08-04
Topics:
Chorghade, Mukund S.
Cseke, Csaba T.
Liu, Paul S.
2,5-Dideoxy-2,5-imino-D-mannitol was synthesized from an arabinofuranose derivative.Mercuric acetate cyclization of an ene-carbamate was the key step.The compound proved to be an inhibitor of the pyrophosphate-fructose-6-phosphate-1-phosphotransferase (PFP) enzyme and has potential utility in the biorational design of herbicides.
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