Synthesis of optically active 4-substituted 2-aminobutyrolactones and homoserines by combined aldol/photocyclization reactions of chromium aminocarbene complexes

Article abstract of DOI:10.1021/ja00101a014

Aldol reactions of optically active chromium aminocarbene complexes proceeded with moderate to high diasteroselectivity. Photolysis of the aldol product gave optically active 4-substituted 2-aminobutyrolactones which could be hydrolyzed to γ-hydroxy-α-ami