Pyrazole-5-carboxamides, novel inhibitors of receptor for advanced glycation end products (RAGE)

DOI: 10.1016/j.ejmech.2014.03.072

Source and publish data:

European Journal of Medicinal Chemistry p. 128 - 142 (2014)

Update date:2022-09-26

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Authors:

Han, Young Taek

Kim, Kyeojin

Choi, Gyeong-In

An, Hongchan

Son, Dohyun

Kim, Hee

Ha, Hee-Jin

Son, Jun-Hyeng

Chung, Suk-Jae

Park, Hyun-Ju

Lee, Jeewoo

Suh, Young-Ger

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Article abstract of DOI:10.1016/j.ejmech.2014.03.072

In an effort to develop novel inhibitors of receptor for advanced glycation end products (RAGE) for the treatment of Alzheimer's disease, a series of pyrazole-5-carboxamides were designed, synthesized and biologically evaluated. Analyses of the extensive

Full text of DOI:10.1016/j.ejmech.2014.03.072

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Product name:ethyl 3-(4-(4-chlorophenoxy)phenyl)-1-propyl-1H-pyrazole-5-carboxylate

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