Stereoselective Synthesis of 9β-Hydroxytaxanes via Reduction with Samarium Diiodide

DOI: 10.1016/0040-4039(95)00142-Y

Source and publish data:

Tetrahedron Letters p. 1783 - 1786 (1995)

Update date:2022-08-03

Topics:

Authors:

Georg, Gunda I.

Cheruvallath, Zacharia S.

Velde, David G. Vander

Himes, Richard H.

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Article abstract of DOI:10.1016/0040-4039(95)00142-Y

Reaction of baccatin III and paclitaxel with samarium diiodide yielded the corresponding 10-deacetyl-9β-hydroxy derivatives.When 10-deacetylbaccatin III and docetaxel were subjected to the same reaction conditions the corresponding 9β-hydroxy and 10-dehyd

Full text of DOI:10.1016/0040-4039(95)00142-Y

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