Determination of the absolute configuration of biologically active (S)-(-)-NB 818 and its structural correlation with the stereoselectivity of the channel blocking action

DOI: 10.1248/cpb.42.1968

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1968 - 1970 (1994)

Update date:2022-07-30

Topics: Enantioselective synthesis X-ray crystallography Stereoselectivity Chirality Structural Correlation Absolute Configuration Patch-clamp electrophysiology

Authors:

Yamazaki

Ebiike Ebiike

Achiwa Achiwa

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1248/cpb.42.1968

The absolute configuration of 4-(2,3-dichlorophenyl)-1,4-dihydropyridines was established by chemical correlation with (S)-(-)-felodipine, the absolute configuration of which had been determined by X-ray analysis.

Full text of DOI:10.1248/cpb.42.1968

NII-Electronic Library Service

Products guided by the article

Product name:(S)-4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-5-pivaloyloxymethoxycarbonyl-3-pyridinecarboxylic acid

Cas No:164263-06-3

R&D Labs maybe for 164263-06-3

KA-SHING Business Trade Macau Co., Ltd.

Contact:00853-28430045

Address:23rd Floor, Block 3 La Cite, Areia Preta, Macao
NanJing Rate Biochemicals CO., LTD

Contact:+86-25-84931986

Address:NO. 1 Hongjing Road,Jiangning Science Park,Nanjing,China
Rudong Zhenfeng Yiyang Chemical Co., Ltd.

Contact:0513-84573047

Address:South Fengli Town, Rudong County, Jiangsu Province, China
jiangsu hualin chemical co.,ltd.

Contact:86-25-87787402

Address:jaingsu,china
Sarchem Laboratories, Inc.

Contact:732.938.2777

Address:5012 Industrial Road Farmingdale, NJ 07727

Relevant to this article

Synthesis of internal olefins by direct coupling of alcohols and olefins over MoΒ zeolite

Doi:10.1016/j.catcom.2019.01.027
(2019)
Ergoline-derived inverse agonists of the human H3 receptor for the treatment of narcolepsy

Doi:10.1002/cmdc.201402055
(2014)
Reductive ring opening of oxygen-containing benzo-fused heterocycles by an arene-catalysed lithiation

Doi:10.1055/s-2004-815971
(2004)
A Convergent Carbohydrate Approach to the Synthesis of Taxol. Part 1. Ring A Subunit

Doi:10.1016/0040-4039(95)00271-D
(1995)
Metallkomplexe mit biologisch wichtigen Liganden LXXVI. Halbsandwichkomplexe von Cobalt(III), Iridium(III) und Ruthenium(II) mit Amiden von 2-Hydroxyiminocarbonsaeuren

Doi:10.1016/0022-328X(94)05257-C
(1995)
Aerobic Enantioselective Epoxidation of Unfunctionalized Olefins Catalyzed by Optically Active Salen-Manganese (III) Complexes

Doi:10.1246/bcsj.67.2248
(1994)

Article Doi