2-Iminohomopiperidinium salts as selective inhibitors of inducible nitric oxide synthase (iNOS)

DOI: 10.1021/jm9704715

Source and publish data:

Journal of Medicinal Chemistry p. 1361 - 1366 (1998)

Update date:2022-07-30

Topics:

Authors:

Hansen Jr., Donald W.

Peterson, Karen B.

Trivedi, Mahima

Kramer, Steven W.

Webber, Ronald K.

Tjoeng, Foe S.

Moore, William M.

Jerome, Gina M.

Kornmeier, Christine M.

Manning, Pamela T.

Connor, Jane R.

Misko, Thomas P.

Currie, Mark G.

Pitzele, Barnett S.

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Article abstract of DOI:10.1021/jm9704715

An attractive approach to the treatment of inflammatory conditions such as osteo- and rheumatoid arthritis, inflammatory bowel disease, and sepsis is through the selective inhibition of human inducible nitric oxide synthase (hiNOS) since localized excess

Full text of DOI:10.1021/jm9704715

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