Journal of Organic Chemistry p. 7334 - 7339 (1995)
Update date:2022-08-03
Topics:
Pommier
Pons
Kocienski
A key step in the first total synthesis of the potent pancreatic lipase inhibitor (-)-lipstatin (1) is a diastereoselective Lewis acid-promoted [2 + 2] cycloaddition reaction between n-hexyl(trimethylsilyl)ketene (4) and (R)-(-)-(Z,Z)-3-[(tert-butyldimethylsilyl)oxy]-5,8-tetradecadienal (3), which is prepared from dimethyl (S)-(-)-malate.
View MoreContact:+86-515-88356562
Address:No.2, West Daqing Road, Yancheng, Jiangsu, China
Hangzhou jls Flame Retardants Chemical Co.,Ltd
Contact:+86-571-87250387/87250386
Address:MOGANSHAN RODA 1418# SHANGCHENG INDUSTRIAL PARK
Xinjiang Zhongtai Chemical Co., Ltd.
Contact:+86-991-8788172
Address:NO.78 XISHAN RD.URUMQI,CHINA
Beijing Green Guardee Technology CO,.LTD
Contact:+86-10-69706062
Address:F2 BLdj,5 No.37 Chaoqian Road
Zhejiang Sucon Silicone Co.,Ltd
Contact:+86-575-88046692
Address:Qisheng Rd., Paojiang Industrial Zone, Shaoxing, Zhejiang, China.
Doi:10.1080/00397919508011826
(1995)Doi:10.1021/acs.orglett.8b00071
(2018)Doi:10.1016/0022-328X(95)00311-D
(1995)Doi:10.1002/chem.202001902
(2020)Doi:10.1021/jacs.7b12673
(2018)Doi:10.1002/jhet.5570320419
(1995)