Synthesis of L-O-Phosphohomoserine and its C-3 Chirally Deuteriated Isotopomers: Probes for the Pyridoxal Phosphate Dependent Threonine Synthase Reaction

DOI: 10.1039/c39940000815

Source and publish data:

Journal of the Chemical Society. Chemical communications p. 815 - 816 (1994)

Update date:2022-08-03

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Authors:

Barclay, Fiona

Chrystal, Ewan

Gani, David

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Article abstract of DOI:10.1039/c39940000815

A short efficient synthesis of the threonine synthase substrate L-O-phosphohomoserine and its C-3 chirally deuteriated isotopomers is described; the route also provides access to L-homoserine and its C-3 chirally deuteriated isotopomers in high yield.

Full text of DOI:10.1039/c39940000815

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