Synthesis of azetidine-type taxanes

DOI: 10.1016/0040-4039(96)00495-9

Source and publish data:

Tetrahedron Letters p. 3203 - 3206 (1996)

Update date:2022-08-05

Topics: Characterization Deprotection Starting Material Purification and Isolation Protection and Functionalization

Authors:

Fenoglio

Nano Nano

Vander Velde

Appendino

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Article abstract of DOI:10.1016/0040-4039(96)00495-9

Starting from the alkaloid 2'-deacetoxyaustrospicatine (2) azetidine isosteres of the oxetane-type laxane 1-deoxy-2-debenzoyloxy-4-deacetylbaccatin VI were synthesized.

Full text of DOI:10.1016/0040-4039(96)00495-9

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Product name:Acetic acid (1R,3S,4S,5S,7S,8S,9R,10R,13S)-7,10,13-triacetoxy-4-(benzyloxyimino-methyl)-4,5-dihydroxy-8,12,15,15-tetramethyl-tricyclo[9.3.1.0^3,8]pentadec-11-en-9-yl ester

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