Highly efficient synthesis of 2-substituted 4H-chromen-4-ones by means of F--induced 6-endo-digonal cyclization of o-(silyloxy)phenyl ethynyl ketone derivatives

Article abstract of DOI:10.1021/jo00095a003

Efficient synthesis of 2-substituted 4H-chromen-4-ones, a core structure of the antitumor antibiotic kapurimycin A₃, was achieved through F^-- induced cyclization of o-(silyloxy)phenyl ethynyl ketone derivatives.