Tetrahedron p. 11307 - 11320 (1996)
Update date:2022-08-03
Topics:
Suau, Rafael
Lopez-Romero, Juan Manuel
Rico, Rodrigo
Alonso, Francisco J.
Lobo, Carolina
The synthesis of cepharadione-B and 2-demethoxy analogues is described. Starting from fluorenones, ring C was formed by cyclization of (biphenyl-2-yl)acetyl morpholines under Bischler-Napieralsky conditions. The photochemistry of chloroacetamides was used to form ring B. The cytotoxicity of these compounds on several tumor cell lines was evaluated.
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