A mild and highly selective N-benzoylation of cytosine and adenine bases in mucleosides with N-benzoyltetrazole

DOI: 10.1016/S0040-4039(97)10423-3

Source and publish data:

Tetrahedron Letters p. 8811 - 8814 (1997)

Update date:2022-07-30

Topics:

Authors:

Bhat, Balkrishen

Sanghvi, Yogesh S.

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Article abstract of DOI:10.1016/S0040-4039(97)10423-3

N-Benzoyltetrazole has been developed as a mild and selective reagent for monobenzoylation of the exocyclic amino group in nucleic acid bases. Its usefulness is demonstrated by protection of adenine and cytosine bases, an important procedure in the nucleic acid chemistry field.

Full text of DOI:10.1016/S0040-4039(97)10423-3

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